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rs403016

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 2x risk for lupus
(C;G) 2x risk for lupus
(G;G) average
ReferenceGRCh37 37.1/131
Chromosome1
Position161518422
GeneFCGR3A
is asnp
is mentioned by
dbSNPrs403016
ebirs403016
HLIrs403016
Exacrs403016
Varsomers403016
Maprs403016
PheGenIrs403016
hapmaprs403016
1000 genomesrs403016
hgdprs403016
ensemblrs403016
gopubmedrs403016
geneviewrs403016
scholarrs403016
googlers403016
pharmgkbrs403016
gwascentralrs403016
openSNPrs403016
23andMers403016
23andMe allrs403016
SNP Nexus

SNPshotrs403016
SNPdbers403016
MSV3drs403016
GWAS Ctlgrs403016
Max Magnitude0
? (C;C) (C;G) (G;G) 28
SNP rs403016 has been reported from a study of 119 Chinese lupus patients to be associated with an increased risk for developing the disease. The odds ratio is 2.2 (p = 0.028). The risk allele is rs403016(G), which encodes the "72R" (R for arginine) allele. [PMID 16716162]
OMIM146740
Desc
Variant0001
Relatedalso

[PMID 17922423] [Study on genetic susceptibility of the single nucleotide polymorphism of FCGR3A gene and systemic lupus erythematosus].


[PMID 18625651] Genetic susceptibility and haplotype analysis between Fcgamma receptor IIB and IIIA gene with systemic lupus erythematosus in Chinese population.

GET Evidence
FCGR3B-S36R
aa_change Ser36Arg
aa_change_short S36R
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.211538
summary