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rs4149081

From SNPedia

Orientationplus
Stabilizedplus
Make rs4149081(A;A)
Make rs4149081(A;G)
Make rs4149081(G;G)
ReferenceGRCh38 38.1/141
Chromosome12
Position21225087
GeneSLCO1B1
is asnp
is mentioned by
dbSNPrs4149081
ebirs4149081
HLIrs4149081
Exacrs4149081
Varsomers4149081
Maprs4149081
PheGenIrs4149081
hapmaprs4149081
1000 genomesrs4149081
hgdprs4149081
ensemblrs4149081
gopubmedrs4149081
geneviewrs4149081
scholarrs4149081
googlers4149081
pharmgkbrs4149081
gwascentralrs4149081
openSNPrs4149081
23andMers4149081
23andMe allrs4149081
SNP Nexus

SNPshotrs4149081
SNPdbers4149081
MSV3drs4149081
GWAS Ctlgrs4149081
GMAF0.2525
Max Magnitude
? (A;A) (A;G) (G;G) 28
[PMID 19901119OA-icon.png] Germline Genetic Variation in an Organic Anion Transporter Polypeptide Associated With Methotrexate Pharmacokinetics and Clinical Effects



[PMID 21387541] Polymorphisms of the SLCO1B1 gene predict methotrexate-related toxicity in childhood acute lymphoblastic leukemia

GWAS snp
PMID [PMID 21886157OA-icon.png]
Trait
Title Human metabolic individuality in biomedical and pharmaceutical research.
Risk Allele A
P-val 3E-22
Odds Ratio 0.2090 None


[PMID 22668755] Intronic variants in SLCO1B1 related to statin-induced myopathy are associated with the low-density lipoprotein cholesterol response to statins in Chinese patients with hyperlipidaemia


GET Evidence
rs4149081
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.158333
summary