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rs4359

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) faster responder
(C;T) slower responder
(T;T) faster responder
ReferenceGRCh38 38.1/141
Chromosome17
Position63494982
GeneACE
is asnp
is mentioned by
dbSNPrs4359
ebirs4359
HLIrs4359
Exacrs4359
Varsomers4359
Maprs4359
PheGenIrs4359
hapmaprs4359
1000 genomesrs4359
hgdprs4359
ensemblrs4359
gopubmedrs4359
geneviewrs4359
scholarrs4359
googlers4359
pharmgkbrs4359
gwascentralrs4359
openSNPrs4359
23andMers4359
23andMe allrs4359
SNP Nexus

SNPshotrs4359
SNPdbers4359
MSV3drs4359
GWAS Ctlgrs4359
GMAF0.4518
Max Magnitude
This SNP in the ACE gene, also known as C17888T, is reported to influence how quickly African Americans respond to the anti-hypertensive drug ramipril. rs4359(C;C) and rs4359(T;T) homozygotes are able to reach lower blood pressure levels upon treatment with ramipril sooner than rs4359(C;T) heterozygotes. The odds ratio reported for this study, comparing both homozygotes to heterozygotes, is 1.49 (CI: 1.01-2.13). [PMID 17885551OA-icon.png]


[PMID 24918908OA-icon.png] Genomic and Metabolomic Profile Associated to Microalbuminuria