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rs4585

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 2 slightly higher (1.35x) odds of good metformin response in type 2 diabetics
(G;T) 2 average response to metformin in type 2 diabetics
(T;T) 1.5 slightly poorer (0.75x) response to metformin in type 2 diabetics
ReferenceGRCh38 38.1/141
Chromosome11
Position108368901
GeneATM, C11orf65
is asnp
is mentioned by
dbSNPrs4585
ebirs4585
HLIrs4585
Exacrs4585
Varsomers4585
Maprs4585
PheGenIrs4585
hapmaprs4585
1000 genomesrs4585
hgdprs4585
ensemblrs4585
gopubmedrs4585
geneviewrs4585
scholarrs4585
googlers4585
pharmgkbrs4585
gwascentralrs4585
openSNPrs4585
23andMers4585
23andMe allrs4585
SNP Nexus

SNPshotrs4585
SNPdbers4585
MSV3drs4585
GWAS Ctlgrs4585
GMAF0.4793
Max Magnitude2

rs4585 has been found to modify the metformin response in patients with type 2 diabetes.[PMID 21186350OA-icon.png]

? (G;G) (G;T) (T;T) 28

[PMID 21058196] Antioxidant vitamins intake, ataxia telangiectasia mutated (ATM) genetic polymorphisms, and breast cancer risk

Metformin Response


[PMID 25196645] Single nucleotide polymorphisms of ataxia telangiectasia mutated and the risk of papillary thyroid carcinoma


[PMID 25759145] ATM Gene Single-Nucleotide Polymorphisms Predict Regimen-Related Gastrointestinal Toxicity in Patients Allografted after Reduced Conditionings