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rs4696480

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;T) 1 preterm birth
Make rs4696480(A;A)
Make rs4696480(T;T)
ReferenceGRCh38 38.1/141
Chromosome4
Position153685974
GeneTLR2
is asnp
is mentioned by
dbSNPrs4696480
ebirs4696480
HLIrs4696480
Exacrs4696480
Varsomers4696480
Maprs4696480
PheGenIrs4696480
hapmaprs4696480
1000 genomesrs4696480
hgdprs4696480
ensemblrs4696480
gopubmedrs4696480
geneviewrs4696480
scholarrs4696480
googlers4696480
pharmgkbrs4696480
gwascentralrs4696480
openSNPrs4696480
23andMers4696480
23andMe allrs4696480
SNP Nexus

SNPshotrs4696480
SNPdbers4696480
MSV3drs4696480
GWAS Ctlgrs4696480
GMAF0.4601
Max Magnitude1
? (A;A) (A;T) (T;T) 28
[PMID 17667860] preterm birth

rs4696480 (T-16934A and Arg753Gln) and rs5743708) (Thr399Ile) earlier birth for infants carrying two (-16934TA/AA and 753ArgGln/GlnGln)


[PMID 20685742] Toll-like receptor 2 and 4 genes influence susceptibility to adverse effects of traffic-related air pollution on childhood asthma


[PMID 21371045] TLR2 polymorphisms influence neonatal regulatory T cells depending on maternal atopy


[PMID 17565608OA-icon.png] Linkage between Toll-like receptor (TLR) 2 promotor and intron polymorphisms: functional effects and relevance to sarcoidosis.


[PMID 18396467OA-icon.png] Genetic variation and haplotype structures of innate immunity genes in eastern India.


[PMID 19029192OA-icon.png] A pooled investigation of Toll-like receptor gene variants and risk of non-Hodgkin lymphoma.


[PMID 19134200OA-icon.png] No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis.


[PMID 19543401OA-icon.png] Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.


[PMID 20113509OA-icon.png] Toll-like receptor 2 gene polymorphisms, pulmonary tuberculosis, and natural killer cell counts.


[PMID 20463618OA-icon.png] Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.


[PMID 20599261] Gene-gene interaction in regulatory T-cell function in atopy and asthma development in childhood.


[PMID 21356257] Toll-like receptor (TLR) 2 promoter and intron 2 polymorphisms are associated with increased risk for spontaneous bacterial peritonitis in liver cirrhosis.


[PMID 21437199OA-icon.png] Toll-like receptor 2 (TLR2) gene polymorphisms are not associated with sarcoidosis in the Japanese population.


[PMID 21500195] The toll-like receptor 2 (TLR2) -196 to -174 del/ins polymorphism affects viral loads and susceptibility to hepatocellular carcinoma in chronic hepatitis C.


[PMID 21872627] Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.


[PMID 23161283OA-icon.png] SNPs in toll-like receptor (TLR) genes as new genetic alterations associated with congenital toxoplasmosis?


[PMID 24971461OA-icon.png] Polymorphisms in the Inflammatory Pathway Genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort


[PMID 25790282OA-icon.png] Combined Effect of TLR2 Gene Polymorphism and Early Life Stress on the Age at Onset of Bipolar Disorders


[PMID 24776844] Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease


[PMID 26846412] Ancestry informative markers and selected single nucleotide polymorphisms in immunoregulatory genes on preterm labor and preterm premature rupture of membranes: a case control study.


[PMID 27155792] TLR2 and TLR4 polymorphisms in Southern Chinese Psoriasis Vulgaris patients.


[PMID 27207565] Toxoplasma gondii exposure may modulate the influence of TLR2 genetic variation on bipolar disorder: a gene-environment interaction study.