rs4775041
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | lowest phosphatidylethanolamine values | |
| (C;G) | intermediate phosphatidylethanolamine values | |
| (G;G) | highest phosphatidylethanolamine values |
| Reference | GRCh38 38.1/141 |
| Chromosome | 15 |
| Position | 58382496 |
| Gene | LOC101928635 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs4775041 |
| dbSNP (classic) | rs4775041 |
| ClinGen | rs4775041 |
| ebi | rs4775041 |
| HLI | rs4775041 |
| Exac | rs4775041 |
| Gnomad | rs4775041 |
| Varsome | rs4775041 |
| LitVar | rs4775041 |
| Map | rs4775041 |
| PheGenI | rs4775041 |
| Biobank | rs4775041 |
| 1000 genomes | rs4775041 |
| hgdp | rs4775041 |
| ensembl | rs4775041 |
| geneview | rs4775041 |
| scholar | rs4775041 |
| rs4775041 | |
| pharmgkb | rs4775041 |
| gwascentral | rs4775041 |
| openSNP | rs4775041 |
| 23andMe | rs4775041 |
| SNPshot | rs4775041 |
| SNPdbe | rs4775041 |
| MSV3d | rs4775041 |
| GWAS Ctlg | rs4775041 |
| GMAF | 0.2112 |
| Max Magnitude | 0 |
| ? | (C;C) (C;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs4775041 is a SNP located near the LIPC gene.
A study of metabolite concentrations in the blood of 284 adult males from Southern Germany determined that several SNPs were associated either directly with a metabolite range or with a ratio of metabolites. The rarer rs4775041(G) allele was associated with increased phosphatidylethanolamine values. 10.1371/journal.pgen.1000282
| GWAS snp | |
|---|---|
| PMID | [PMID 19043545 ]
|
| Trait | Serum metabolites |
| Title | Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum |
| Risk Allele | |
| P-val | 1E-7 |
| Odds Ratio | NR NR |
| GWAS snp | |
|---|---|
| PMID | [PMID 18193043]
|
| Trait | HDL cholesterol |
| Title | Newly identified loci that influence lipid concentrations and risk of coronary artery disease |
| Risk Allele | C |
| P-val | 3.0000000000000003E-20 |
| Odds Ratio | 1.38 [NR] mg/dl higher |
[PMID 18852197] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
[PMID 19041386] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.
[PMID 19060910] Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
[PMID 19060911] Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
[PMID 19148283] Genetic differences between the determinants of lipid profile phenotypes in African and European Americans: the Jackson Heart Study.
[PMID 19299407] Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample.
[PMID 19435741] Common lipid-altering gene variants are associated with therapeutic intervention thresholds of lipid levels in older people.
[PMID 19656773] A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.
[PMID 19734193] Polymorphisms in the hepatic lipase gene affect plasma HDL-cholesterol levels in a Turkish population.
[PMID 20339536] Genome-wide association of lipid-lowering response to statins in combined study populations.
[PMID 23150898] Evaluation of seven common lipid associated loci in a large Indian sib pair study
[PMID 31910446] Genome-wide association study of metabolic syndrome in Korean populations.
