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rs5400

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 0.1 normal sugar consumption
(C;T) 1.7 significantly higher sugar consumption?
(T;T) 1.8 significantly higher sugar consumption
ReferenceGRCh38 38.1/142
Chromosome3
Position171014511
GeneSLC2A2
is asnp
is mentioned by
dbSNPrs5400
ebirs5400
HLIrs5400
Exacrs5400
Varsomers5400
Maprs5400
PheGenIrs5400
hapmaprs5400
1000 genomesrs5400
hgdprs5400
ensemblrs5400
gopubmedrs5400
geneviewrs5400
scholarrs5400
googlers5400
pharmgkbrs5400
gwascentralrs5400
openSNPrs5400
23andMers5400
23andMe allrs5400
SNP Nexus

SNPshotrs5400
SNPdbers5400
MSV3drs5400
GWAS Ctlgrs5400
GMAF0.1873
Max Magnitude1.8
? (C;C) (C;T) (T;T) 28
[PMID 18349384] rs5400(T;T) carriers had a significantly higher intake of sugars

blog discussion


[PMID 18678618OA-icon.png] Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes.


[PMID 20066028OA-icon.png] Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels.


[PMID 20142250OA-icon.png] Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study.


[PMID 21283750OA-icon.png] Studies of the association of Arg72Pro of tumor suppressor protein p53 with type 2 diabetes in a combined analysis of 55,521 Europeans.


GET Evidence
SLC2A2-T110I
aa_change Thr110Ile
aa_change_short T110I
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.240193
summary



Food Preference


ClinVar
Risk rs5400(T;T)
Alt rs5400(T;T)
Reference rs5400(C;C)
Significance Probable-non-pathogenic
Disease not specified
Variation info
Gene SLC2A2
CLNDBN not specified
Reversed 1
HGVS NC_000003.11:g.170732300G>A
CLNSRC ClinVar University of Chicago
CLNACC RCV000118387.2,



[PMID 26112465] GLUT2 and TAS1R2 Polymorphisms and Susceptibility to Dental Caries