|?|| (A;A) (A;G) (G;G) ||28|
] Three (rs643627
: A-C-T), two (rs594242
: C-T) and a single functional (rs6311
: T) marker were protective against suicidal behavior.
The complementary makers (rs594242-rs6311: G-C and rs6311: C) were associated with increased risk for non-violent and impulsive suicidal behavior.
Furthermore, CC-homozygotes for the functional SNP rs6311 reported more anger- and aggression-related behavior.
[PMID 20827275] Influence of HTR2A polymorphisms and parental rearing on personality traits in healthy Japanese subjects
Genetic evaluation of the serotonergic system in chronic fatigue syndrome.[PMID 18079067] Found that this is in linkage disequilibrium with rs655888.
[PMID 17590256] 5-HT2A SNPs and the Temperament and Character Inventory.
[PMID 26544898] The impact of serotonin receptor 1A and 2A gene polymorphisms and interactions on suicide attempt and suicide risk in depressed patients with insufficient response to treatment - a European multicentre study