Have questions? Visit https://www.reddit.com/r/SNPedia

rs7003908

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) normal
(A;C) normal
(C;C) 1.4x increased risk for glioblastoma
ReferenceGRCh38 38.1/141
Chromosome8
Position47858141
GenePRKDC
is asnp
is mentioned by
dbSNPrs7003908
ebirs7003908
HLIrs7003908
Exacrs7003908
Varsomers7003908
Maprs7003908
PheGenIrs7003908
hapmaprs7003908
1000 genomesrs7003908
hgdprs7003908
ensemblrs7003908
gopubmedrs7003908
geneviewrs7003908
scholarrs7003908
googlers7003908
pharmgkbrs7003908
gwascentralrs7003908
openSNPrs7003908
23andMers7003908
23andMe allrs7003908
SNP Nexus

SNPshotrs7003908
SNPdbers7003908
MSV3drs7003908
GWAS Ctlgrs7003908
GMAF0.2906
Max Magnitude
? (A;A) (A;C) (C;C) 28
A study of 1,000 glioblastoma multiforme cases and 2,000 controls in the US concluded that the PRKDC gene rs7003908(C;C) genotype was associated with an increase in risk for glioblastoma multiforme (odds ratio 1.44, CI: 1.13-1.84).[PMID 19318434OA-icon.png]


[PMID 19815090] The Relation between Endothelial Nitric Oxide Synthase Gene Variants and Primary Open-Angle Glaucoma: Interactions with Gender and Postmenopausal Hormone Use


[PMID 20590474] Polymorphic Variants of DNA Repair Gene XRCC3 and XRCC7 and Risk of Prostate Cancer: A Study from North Indian Population


[PMID 22634101] Genetic variation in DNA repair gene XRCC7 (G6721T) and susceptibility to breast cancer


[PMID 16400611OA-icon.png] Genomewide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample.


[PMID 23437280OA-icon.png] Comprehensive SNP scan of DNA repair and DNA damage response genes reveal multiple susceptibility Loci conferring risk to tobacco associated leukoplakia and oral cancer


[PMID 23108991] Current evidence on the relationship between three polymorphisms in the XRCC7 gene and cancer risk.


[PMID 26974709] Polymorphisms in double strand break repair related genes influence radiosensitivity phenotype in lymphocytes from healthy individuals.