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rs7105934

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2.1 0.48 times lower odds of developing renal cell carcinoma
(A;G) 2 0.69 times lower odds of developing renal cell carcinoma
(G;G) 0 common in complete genomics
ReferenceGRCh38 38.1/141
Chromosome11
Position69424973
GeneTRAJ57
is asnp
is mentioned by
dbSNPrs7105934
ebirs7105934
HLIrs7105934
Exacrs7105934
Varsomers7105934
Maprs7105934
PheGenIrs7105934
hapmaprs7105934
1000 genomesrs7105934
hgdprs7105934
ensemblrs7105934
gopubmedrs7105934
geneviewrs7105934
scholarrs7105934
googlers7105934
pharmgkbrs7105934
gwascentralrs7105934
openSNPrs7105934
23andMers7105934
23andMe allrs7105934
SNP Nexus

SNPshotrs7105934
SNPdbers7105934
MSV3drs7105934
GWAS Ctlgrs7105934
GMAF0.2052
Max Magnitude2.1
? (A;A) (A;G) (G;G) 28
CPMC Logo.png

This SNP has been recognized by the Coriell Personalized Medicine Collaborative ICOB.
Additional information is available here

GWAS snp
PMID [PMID 21131975OA-icon.png]
Trait
Title Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3
Risk Allele
P-val 8E-14
Odds Ratio 1.4500 [1.32-1.61]

23andMe reports that each A allele at rs7105934 is associated with 0.69 times lower odds of developing renal cell carcinoma (a form of kidney cancer). [PMID 21131975OA-icon.png]


[PMID 22131124] Chromosome 11q13.3 variant modifies renal cell cancer risk in a Chinese population


[PMID 23911636] Germline genetic variations at 11q13 and 12p11 locus modulate age of onset for renal cell carcinoma


[PMID 24220910OA-icon.png] A genome-wide association study of renal cell carcinoma among African Americans