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From SNPedia

Geno Mag Summary
(T;T) 0 common on affy axiom data
Make rs763780(C;C)
Make rs763780(C;T)
ReferenceGRCh38 38.1/141
is asnp
is mentioned by
1000 genomesrs763780
23andMe allrs763780
SNP Nexus

GWAS Ctlgrs763780
Max Magnitude0
? (C;C) (C;T) (T;T) 28

No association seen in the following report:

[PMID 19414056] Genetic polymorphism of interleukin-17A and -17F genes in gastric carcinogenesis

[PMID 19724898] Effect of polymorphisms of IL-17A, -17F and MIF genes on CpG island hyper-methylation (CIHM) in the human gastric mucosa

[PMID 21615796] Interleukin-17F gene polymorphism in patients with chronic immune thrombocytopenia

[PMID 22118860] Interleukin 17 gene polymorphism is associated with anti-aquaporin 4 antibody-positive neuromyelitis optica in the Southern Han Chinese - A case control study

[PMID 22142827OA-icon.png] A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303

[PMID 22312940] Interleukin 17A and F and asthma in Saudi Arabia: gene polymorphisms and protein levels.

[PMID 16630936] IL-17F sequence variant (His161Arg) is associated with protection against asthma and antagonizes wild-type IL-17F activity.

[PMID 17828618] The influence of polymorphisms of interleukin-17A and interleukin-17F genes on the susceptibility to ulcerative colitis.

[PMID 18774769] Lower frequency of IL-17F sequence variant (His161Arg) in chronic fatigue syndrome patients.

[PMID 20618772] Association between IL-17F gene polymorphisms and susceptibility to and severity of rheumatoid arthritis (RA).

[PMID 20620187] Interleukin-17 gene polymorphism is associated with Vogt-Koyanagi-Harada syndrome but not with Behcet's disease in a Chinese Han population.

[PMID 22692973] Interleukin-17 gene polymorphisms are associated with bladder cancer in a Chinese Han population.

[PMID 23049595OA-icon.png] Association between IL17 Polymorphisms and Risk of Cervical Cancer in Chinese Women

GET Evidence
aa_change His161Arg
aa_change_short H161R
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.0630229

[PMID 23111159] Genetic association between IL-17F gene polymorphisms and the pathogenesis of Graves' Disease in the Han Chinese population

[PMID 23376081] Analysis of IL-17 gene polymorphisms in Chinese patients with dilated cardiomyopathy

[PMID 23519962] Association of Interleukin-17F Gene Polymorphism with Enterovirus 71 Encephalitis in Patients with Hand, Foot, and Mouth Disease

[PMID 23652560] Genetic polymorphisms of interleukin 17A and interleukin 17F and their association with inflammatory bowel disease in a Chinese Han population

[PMID 23137879] Evaluation of IL17A expression and of IL17A, IL17F and IL23R gene polymorphisms in Brazilian individuals with periodontitis

[PMID 24164796] Interleukin-17F single-nucleotide polymorphism (7488T>C) and its association with susceptibility to leprosy

[PMID 24315816] Effect of interleukin-17A and interleukin-17F gene polymorphisms on the risk of gastric cancer in a Chinese population

[PMID 22573572] Phenotype-genotype profiles in Crohn's disease predicted by genetic markers in autophagy-related genes (GOIA study II).

[PMID 22579472] The IL6 gene polymorphism -634C>G and IL17F gene polymorphism 7488T>C influence bone mineral density in young and elderly Japanese women.

[PMID 22816799] Association of interleukin-17A and -17F gene single-nucleotide polymorphisms with autoimmune thyroid diseases.

[PMID 23219503] The IL-17F sequence variant is associated with susceptibility to tuberculosis.

[PMID 24857622] IL-17F but not IL-17A gene polymorphism confers risk to multiple sclerosis in a Chinese Han population

[PMID 24935327] Haplotype Analysis on Chromosome 6p of Tumor Necrosis Factor Alpha, Vascular Endothelial Growth Factor A, and Interleukin-17F Alleles Associated With Corneal Transplant Rejection

[PMID 25012243] IL-17 gene polymorphism is associated with susceptibility to gastric cancer

[PMID 25227691OA-icon.png] Association of IL-17A and IL-17 F gene polymorphisms with recurrent pregnancy loss in Iranian women

[PMID 25374195] Meta-analysis of Associations between Interleukin-17 Gene Polymorphisms and Risk of Gastric Cancer

[PMID 25680555] Interleukin-17FT7488 allele is associated with a decreased risk of colorectal cancer and tumor progression

[PMID 25857634] Genetic Polymorphisms in the Toll-like Receptor 10, Interleukin (IL)17A and IL17F genes differently affect the risk for Tuberculosis in Croatian population

[PMID 26339129OA-icon.png] The Influence of Interleukin 17A and IL17F Polymorphisms on Chronic Periodontitis Disease in Brazilian Patients

[PMID 26337284] Association study between IL-17A and IL-17F gene polymorphism and myasthenia gravis in Chinese patients

[PMID 26400516] Interleukin-17 gene polymorphisms in patients with post-transplant diabetes mellitus

[PMID 26436389] Correlation between polymorphisms in the IL-17A and IL-17F genes and development of coronary artery disease

[PMID 26447633] Influence of the IL17A and IL17F genes polymorphisms on the long-term kidney allograft function and return to dialysis after kidney transplantation

[PMID 26467330] Interleukin-17 and leptin genes polymorphisms and their levels in relation to recurrent pregnancy loss in Egyptian females

[PMID 26515887] Interleukin-17A rs2275913, Interleukin-17F rs763780 and rs2397084 gene polymorphisms as possible risk factors in Juvenile lupus and lupus related nephritis

[PMID 26535650] Role of IL-17 gene polymorphisms in the susceptibility to gastric cancer

[PMID 26535675] Association analysis of rs2275913G>A and rs763780T>C interleukin 17 polymorphisms in Chinese women with cervical cancer

[PMID 26546176] Association of IL-17A and IL-17F gene polymorphisms with chronic hepatitis B and hepatitis B virus-related liver cirrhosis in a Chinese population: A case-control study

[PMID 26550210OA-icon.png] Association between IL-17F rs763780 polymorphism and susceptibility of asthma: a meta-analysis