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rs7757037

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0.63x decreased risk for bipolar disorder
(A;G) 0.68x decreased risk for bipolar disorder
(G;G) 0 normal
ReferenceGRCh38 38.1/141
Chromosome6
Position35580459
GeneFKBP5, LOC101929309
is asnp
is mentioned by
dbSNPrs7757037
ebirs7757037
HLIrs7757037
Exacrs7757037
Varsomers7757037
Maprs7757037
PheGenIrs7757037
hapmaprs7757037
1000 genomesrs7757037
hgdprs7757037
ensemblrs7757037
gopubmedrs7757037
geneviewrs7757037
scholarrs7757037
googlers7757037
pharmgkbrs7757037
gwascentralrs7757037
openSNPrs7757037
23andMers7757037
23andMe allrs7757037
SNP Nexus

SNPshotrs7757037
SNPdbers7757037
MSV3drs7757037
GWAS Ctlgrs7757037
GMAF0.4991
Max Magnitude0
? (A;A) (A;G) (G;G) 28
rs7757037, a SNP in the FKBP5 gene, is associated with increased risk for bipolar disorder in a study of 500+ Caucasian patients.

The most common allele, rs7757037(G), was associated with highest risk. Giving that allele a relative odds ratio of 1.0, the odds for the (A;G) and (A;A) genotypes were 0.68x (CI:0.53-0.87, p=0.007) and 0.63x (CI: 0.45-0.89, p=0.007).[PMID 18180755OA-icon.png]