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rs7927894

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 2 0.83x lower risk of Atopic Dermatitis.
(C;T) 1.9 Normal risk of Atopic Dermatitis.
(T;T) 2 1.2x higher risk of Atopic Dermatitis.
ReferenceGRCh38 38.1/141
Chromosome11
Position76590272
is asnp
is mentioned by
dbSNPrs7927894
ebirs7927894
HLIrs7927894
Exacrs7927894
Varsomers7927894
Maprs7927894
PheGenIrs7927894
hapmaprs7927894
1000 genomesrs7927894
hgdprs7927894
ensemblrs7927894
gopubmedrs7927894
geneviewrs7927894
scholarrs7927894
googlers7927894
pharmgkbrs7927894
gwascentralrs7927894
openSNPrs7927894
23andMers7927894
23andMe allrs7927894
SNP Nexus

SNPshotrs7927894
SNPdbers7927894
MSV3drs7927894
GWAS Ctlgrs7927894
GMAF0.2819
Max Magnitude2
? (C;C) (C;T) (T;T) 28

23andMe blog associated rs7927894(T) with Crohn’s disease 1.16x and atopic dermatitis

GWAS snp
PMID [PMID 19349984]
Trait Atopic dermatitis
Title A common variant on chromosome 11q13 is associated with atopic dermatitis
Risk Allele A
P-val 8E-10
Odds Ratio
GWAS snp
PMID [PMID 18587394OA-icon.png]
Trait Crohn's disease
Title Genome-wide assocation defines more than 30 distinct susceptibility loci for Crohn's disease
Risk Allele T
P-val 1.0000000000000001E-9
Odds Ratio 1.16 [NR]



[PMID 20109745OA-icon.png] Chromosome 11q13.5 variant associated with childhood eczema: An effect supplementary to filaggrin mutations


[PMID 20706116] Genome-wide approaches to the etiology of eczema

OMIM613064
Desc
Variant
Relatedalso
[PMID 21752155OA-icon.png] Genetic susceptibility to inflammation and colonic transit in lower functional gastrointestinal disorders: preliminary analysis


[PMID 22197932OA-icon.png] Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis


[PMID 19068216OA-icon.png] Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship.


[PMID 21304977OA-icon.png] An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.


[PMID 21429916] The eczema risk variant on chromosome 11q13 (rs7927894) in the population-based ALSPAC cohort: a novel susceptibility factor for asthma and hay fever.


GET Evidence
rs7927894
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.328125
summary



[PMID 23557745] Association of the chromosome 11q13.5 variant with atopic dermatitis in Austrian patients