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rs8055236

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0
(G;G) 1.7 common, but 2.2x higher risk for heart disease
(G;T) 1.7 1.9x risk for heart disease
(T;T) 0 normal
ReferenceGRCh38 38.1/141
Chromosome16
Position83178793
GeneCDH13
is asnp
is mentioned by
dbSNPrs8055236
ebirs8055236
HLIrs8055236
Exacrs8055236
Varsomers8055236
Maprs8055236
PheGenIrs8055236
hapmaprs8055236
1000 genomesrs8055236
hgdprs8055236
ensemblrs8055236
gopubmedrs8055236
geneviewrs8055236
scholarrs8055236
googlers8055236
pharmgkbrs8055236
gwascentralrs8055236
openSNPrs8055236
23andMers8055236
23andMe allrs8055236
SNP Nexus

SNPshotrs8055236
SNPdbers8055236
MSV3drs8055236
GWAS Ctlgrs8055236
GMAF0.2447
Max Magnitude1.7
? (G;G) (G;T) (T;T) 28
rs8055236 has been reported in a large study to be associated with heart disease, in particular, coronary artery disease.

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with heterozygotes is 1.91 (CI 1.33-2.74), and for homozygotes, 2.23 (CI 1.56-3.17). [PMID 17554300OA-icon.png]

GWAS
SNP rs8055236
PubMedID [PMID 17554300OA-icon.png]
Condition Coronary disease
Gene NR
Risk Allele G
pValue 6.00E-006
OR 1.91
95% CI 1.33-2.74



[PMID 19956433OA-icon.png] Genetics of coronary artery disease: focus on genome-wide association studies.


[PMID 20017983OA-icon.png] Evaluation of population impact of candidate polymorphisms for coronary heart disease in the Framingham Heart Study Offspring Cohort.


GET Evidence
rs8055236
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.34375
summary