Have questions? Visit https://www.reddit.com/r/SNPedia

rs890293

From SNPedia

Orientationminus
Stabilizedplus
Geno Mag Summary
(C;C) 0
Make rs890293(G;G)
Make rs890293(G;T)
Make rs890293(T;T)
ReferenceGRCh38 38.1/142
Chromosome1
Position59926822
GeneCYP2J2
is asnp
is mentioned by
dbSNPrs890293
ebirs890293
HLIrs890293
Exacrs890293
Varsomers890293
Maprs890293
PheGenIrs890293
hapmaprs890293
1000 genomesrs890293
hgdprs890293
ensemblrs890293
gopubmedrs890293
geneviewrs890293
scholarrs890293
googlers890293
pharmgkbrs890293
gwascentralrs890293
openSNPrs890293
23andMers890293
23andMe allrs890293
SNP Nexus

SNPshotrs890293
SNPdbers890293
MSV3drs890293
GWAS Ctlgrs890293
GMAF0.07346
Max Magnitude0
Important Variant Information for CYP2J2. involved in metabolism of some drugs.

rs890293, also known as -50C>T, is a SNP in the CYP2J2 gene.

A study of 5,740 participants of the cardiovascular cohort of the 'Malmö Diet and Cancer' study was monitored for cardiovascular events over 10 years, with the conclusion being there was no significant association between this SNP and either hypertension or ischemic events.[PMID 19851119]



[PMID 20140850] Genetic Variation in the G-50T Polymorphism of the Cytochrome P450 Epoxygenase CYP2J2 Gene and the Risk of Younger Onset Type 2 Diabetes among Chinese Population: Potential Interaction with Body Mass Index and Family History


[PMID 18769365OA-icon.png] Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease.


GET Evidence
rs890293
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.0833333
summary



[PMID 23684773] A Novel Polymorphism of the CYP2J2 Gene is Associated with Coronary Artery Disease in Uygur Population in China


[PMID 25796175] CYP2J2 rs890293 polymorphism is associated with susceptibility to Alzheimer's disease in the Chinese Han population


[PMID 27396818] Gene- gene Interaction between CYP2J2 and PPAR -γ gene on Late-Onset Alzheimer's disease in the eastern Chinese Han Population.