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rs9296249

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) <0.62x risk for restless legs
(C;T) 0.62x risk for restless legs
(T;T) 0 common
ReferenceGRCh38 38.1/141
Chromosome6
Position38398065
GeneBTBD9
is asnp
is mentioned by
dbSNPrs9296249
ebirs9296249
HLIrs9296249
Exacrs9296249
Varsomers9296249
Maprs9296249
PheGenIrs9296249
hapmaprs9296249
1000 genomesrs9296249
hgdprs9296249
ensemblrs9296249
gopubmedrs9296249
geneviewrs9296249
scholarrs9296249
googlers9296249
pharmgkbrs9296249
gwascentralrs9296249
openSNPrs9296249
23andMers9296249
23andMe allrs9296249
SNP Nexus

SNPshotrs9296249
SNPdbers9296249
MSV3drs9296249
GWAS Ctlgrs9296249
GMAF0.3815
Max Magnitude0
? (C;C) (C;T) (T;T) 28
rs9296249, a SNP located in the BTBD9 gene region, has been linked to a lower frequency of restless legs syndrome, a common sleep disorder, with an overall odds ratio of 0.62 (CI: 0.52-0.75) for the (C) minor allele. [PMID 17637780]
Neighborrs9357271
Distance32
GWAS
SNP rs9296249
PubMedID [PMID 17637780]
Condition Restless legs syndrome
Gene BTBD9
Risk Allele T
pValue 4.00E-018
OR 1.67
95% CI 1.49-1.89


OMIM611185
DescRESTLESS LEGS SYNDROME, SUSCEPTIBILITY TO, 6
Variant
Relatedalso

[PMID 19223043] Exploring the genetic link between RLS and ADHD




[PMID 19279021OA-icon.png] Replication of restless legs syndrome loci in three European populations.


GET Evidence
rs9296249
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.3125
summary



[PMID 22914617] Analysis of the BTBD9 and HTR2C variants in Chinese Han patients with Tourette syndrome.