rs10988802
From SNPedia
| Associated with Chemerin Plasma Levels |
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 0 | common in complete genomics |
| Make rs10988802(A;A) |
| Make rs10988802(A;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 9 |
| Position | 95614417 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs10988802 |
| dbSNP (classic) | rs10988802 |
| ClinGen | rs10988802 |
| ebi | rs10988802 |
| HLI | rs10988802 |
| Exac | rs10988802 |
| Gnomad | rs10988802 |
| Varsome | rs10988802 |
| LitVar | rs10988802 |
| Map | rs10988802 |
| PheGenI | rs10988802 |
| Biobank | rs10988802 |
| 1000 genomes | rs10988802 |
| hgdp | rs10988802 |
| ensembl | rs10988802 |
| geneview | rs10988802 |
| scholar | rs10988802 |
| rs10988802 | |
| pharmgkb | rs10988802 |
| gwascentral | rs10988802 |
| openSNP | rs10988802 |
| 23andMe | rs10988802 |
| SNPshot | rs10988802 |
| SNPdbe | rs10988802 |
| MSV3d | rs10988802 |
| GWAS Ctlg | rs10988802 |
| GMAF | 0.1703 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 20237162 ]
|
| Trait | Plasma chemerin levels |
| Title | Chemerin, a Novel Adipokine in the Regulation of Angiogenesis |
| Risk Allele | |
| P-val | 0.000004 |
| Odds Ratio | None None |
rs10988802 is a SNP located in the PTCH1 gene. This gene is a member of the patched gene family and a receptor for sonic hedgehog. This gene functions as a tumor suppressor and has a role during embryonic development. Other SNPs in this gene have been associated with various cancers.
rs10988802 was strongly associated with plasma chemerin levels in a genome-wide association study involving 525 patients from the San Antonio Family Heart Study Cohort, originally described here [PMID 20237162].
Chemerin, also known as retinoic acid receptor responder protein 2 is thought to promote angiogenesis within expanding adipose tissue.
