rs13254738

Associated with prostate cancer risk

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;C)	2	1.18x prostate cancer risk
(C;C)	2	1.18x prostate cancer risk

Make rs13254738(A;A)

Reference

GRCh38 38.1/141

Chromosome

8

Position

127092098

Gene

PRNCR1

is a	snp
is	mentioned by
dbSNP	rs13254738
dbSNP (classic)	rs13254738
ClinGen	rs13254738
ebi	rs13254738
HLI	rs13254738
Exac	rs13254738
Gnomad	rs13254738
Varsome	rs13254738
LitVar	rs13254738
Map	rs13254738
PheGenI	rs13254738
Biobank	rs13254738
1000 genomes	rs13254738
hgdp	rs13254738
ensembl	rs13254738
geneview	rs13254738
scholar	rs13254738
google	rs13254738
pharmgkb	rs13254738
gwascentral	rs13254738
openSNP	rs13254738
23andMe	rs13254738
SNPshot	rs13254738
SNPdbe	rs13254738
MSV3d	rs13254738
GWAS Ctlg	rs13254738

GMAF

0.4752

Max Magnitude

2

?	(A;A) (A;C) (C;C)	28

rs13254738 increases susceptibility to Prostate cancer 1.18 times for carriers of the C allele [PMID 17401364]

[PMID 19549807] Prostate Cancer Risk Associated Loci in African Americans

[PMID 21051319] Risk of Urinary Bladder Cancer is Associated with 8q24 Variant rs9642880[T]: Results from the Los Angeles-Shanghai Case-Control Study

[PMID 22549899] Genetic polymorphism and prostate cancer aggressiveness: A case-only study of 1,536 GWAS and candidate SNPs in African-Americans and European-Americans

[PMID 17618282] A common genetic risk factor for colorectal and prostate cancer.

[PMID 18231127] 8q24 and prostate cancer: association with advanced disease and meta-analysis.

[PMID 18360876] Chromosome 8q24 markers: risk of early-onset and familial prostate cancer.

[PMID 18373104] Genetic variants in the 8q24 locus and risk of testicular germ cell tumors.

[PMID 18535017] Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk.

[PMID 18577746] Multiple loci with different cancer specificities within the 8q24 gene desert.

[PMID 19366828] Evaluation of 8q24 and 17q risk loci and prostate cancer mortality.

[PMID 19549893] Evaluation of the 8q24 prostate cancer risk locus and MYC expression.

[PMID 19602258] Significance of common variants on human chromosome 8q24 in relation to the risk of prostate cancer in native Japanese men.

[PMID 19690179] Functional and clinical significance of variants localized to 8q24 in colon cancer.

[PMID 20039378] Estimation of genotype relative risks from pedigree data by retrospective likelihoods.

[PMID 22382457] Racial disparities in the association between variants on 8q24 and prostate cancer: a systematic review and meta-analysis.

GWAS snp
PMID	[PMID 22923026]
Trait	Prostate cancer
Title	Evaluating genetic risk for prostate cancer among Japanese and Latinos.
Risk Allele	C
P-val	4E-10
Odds Ratio	1.59 [1.38-1.84]

[PMID 22848671] Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.