rs13293564

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(G;G)		1.63x increased nephropathy risk among type-1 diabetics
(G;T)	0	normal
(T;T)		normal

Reference

GRCh38 38.1/141

Chromosome

9

Position

35166766

Gene

UNC13B

is a	snp
is	mentioned by
dbSNP	rs13293564
dbSNP (classic)	rs13293564
ClinGen	rs13293564
ebi	rs13293564
HLI	rs13293564
Exac	rs13293564
Gnomad	rs13293564
Varsome	rs13293564
LitVar	rs13293564
Map	rs13293564
PheGenI	rs13293564
Biobank	rs13293564
1000 genomes	rs13293564
hgdp	rs13293564
ensembl	rs13293564
geneview	rs13293564
scholar	rs13293564
google	rs13293564
pharmgkb	rs13293564
gwascentral	rs13293564
openSNP	rs13293564
23andMe	rs13293564
SNPshot	rs13293564
SNPdbe	rs13293564
MSV3d	rs13293564
GWAS Ctlg	rs13293564

GMAF

0.3581

Max Magnitude

0

?	(G;G) (G;T) (T;T)	28

[PMID 18633107] rs2281999 and rs13293564 (G/T) diabetic nephropathy type-1 diabetes case/control (1176/1323) study from 3 European populations

• odds ratio (OR) for DN associated with the TT genotype was 1.68 [95%CI, 1.29 - 2.19], p = 1.0 10(-4))

replicated in an independent population of 412 cases and 614 controls, (combined OR of 1.63 [CI: 1.30 - 2.05], p = 2.3 10(-5))

[PMID 20687937] Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus

[PMID 31713534] The Association of UNC13B Gene Polymorphisms and Diabetic Kidney Disease in a Chinese Han Population.