rs1585215
From SNPedia
Orientation | minus |
Stabilized | minus |
Geno | Mag | Summary |
---|---|---|
(A;A) | 0 | normal |
(A;G) | 2 | 2x increased risk for Hodgkin lymphoma |
(G;G) | 2.1 | 3.5x increased risk for Hodgkin lymphoma |
Reference | GRCh38 38.1/141 |
Chromosome | 4 |
Position | 102523317 |
Gene | NFKB1 |
is a | snp |
is | mentioned by |
dbSNP | rs1585215 |
dbSNP (classic) | rs1585215 |
ClinGen | rs1585215 |
ebi | rs1585215 |
HLI | rs1585215 |
Exac | rs1585215 |
Gnomad | rs1585215 |
Varsome | rs1585215 |
LitVar | rs1585215 |
Map | rs1585215 |
PheGenI | rs1585215 |
Biobank | rs1585215 |
1000 genomes | rs1585215 |
hgdp | rs1585215 |
ensembl | rs1585215 |
geneview | rs1585215 |
scholar | rs1585215 |
rs1585215 | |
pharmgkb | rs1585215 |
gwascentral | rs1585215 |
openSNP | rs1585215 |
23andMe | rs1585215 |
SNPshot | rs1585215 |
SNPdbe | rs1585215 |
MSV3d | rs1585215 |
GWAS Ctlg | rs1585215 |
GMAF | 0.292 |
Max Magnitude | 2.1 |
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
rs1585215 is a SNP in the NFKB1 gene.
A population-based case-control study including 473 cases of Hodgkin lymphoma concluded that increased risk for the disease was significantly associated with rs1585215. The odds ratio for rs1585215(G;G) homozygotes was 3.5 (CI: 2.2-5.7, Ptrend = 1.7 x 10(-8)), and for (A;G) heterozygotes, 2.1 (CI: 1.5-2.9).[PMID 19223558]
[PMID 25422198] Polymorphic variation of inflammation-related genes and risk of non-Hodgkin lymphoma for Uygur and Han Chinese in Xinjiang