rs1801195

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(G;G)	0	common in clinvar

Make rs1801195(G;T)

Make rs1801195(T;T)

Reference

GRCh38 38.1/141

Chromosome

8

Position

31141764

Gene

WRN

is a	snp
is	mentioned by
dbSNP	rs1801195
dbSNP (classic)	rs1801195
ClinGen	rs1801195
ebi	rs1801195
HLI	rs1801195
Exac	rs1801195
Gnomad	rs1801195
Varsome	rs1801195
LitVar	rs1801195
Map	rs1801195
PheGenI	rs1801195
Biobank	rs1801195
1000 genomes	rs1801195
hgdp	rs1801195
ensembl	rs1801195
geneview	rs1801195
scholar	rs1801195
google	rs1801195
pharmgkb	rs1801195
gwascentral	rs1801195
openSNP	rs1801195
23andMe	rs1801195
SNPshot	rs1801195
SNPdbe	rs1801195
MSV3d	rs1801195
GWAS Ctlg	rs1801195

Merged from

Rs2725362

GMAF

0.4706

Max Magnitude

0

?	(G;G) (G;T) (T;T)	28

[PMID 16857995] Risk of non-Hodgkin lymphoma (NHL) in relation to germline variation in DNA repair and related genes.

[PMID 17366557] A genome-wide linkage scan for cleft lip and cleft palate identifies a novel locus on 8p11-23.

[PMID 18194558] A hierarchical and modular approach to the discovery of robust associations in genome-wide association studies from pooled DNA samples.

[PMID 18978339] Large-scale evaluation of candidate genes identifies associations between DNA repair and genomic maintenance and development of benzene hematotoxicity.

[PMID 19945966] Colorectal cancer and polymorphisms in DNA repair genes WRN, RMI1 and BLM. [PMID 23619945] Polymorphisms in DNA repair pathway genes, body mass index, and risk of non-Hodgkin lymphoma.

ClinVar
Risk	rs1801195(T;T)
Alt	rs1801195(T;T)
Reference	Rs1801195(G;G)
Significance	Other
Disease	not specified Werner syndrome
Variation	info
Gene	WRN
CLNDBN	not specified Werner syndrome
Reversed	0
HGVS	NC_000008.10:g.30999280G>T
CLNSRC	UniProtKB (protein)
CLNACC	RCV000118877.4, RCV000281792.1,

[PMID 29689049] Allelic interaction effects of DNA damage and repair genes on the predisposition to age-related cataract.

[PMID 31333776] Associations of mRNA expression of DNA repair genes and genetic polymorphisms with cancer risk: a bioinformatics analysis and meta-analysis.