rs2352028

plus

Geno	Mag	Summary
(C;C)	0
(C;T)	2
(T;T)	2	Increased risk of lung cancer in non-smokers and never smokers

Reference

GRCh38 38.1/141

Chromosome

13

Position

91792975

Gene

GPC5

is a	snp
is	mentioned by
dbSNP	rs2352028
dbSNP (classic)	rs2352028
ClinGen	rs2352028
ebi	rs2352028
HLI	rs2352028
Exac	rs2352028
Gnomad	rs2352028
Varsome	rs2352028
LitVar	rs2352028
Map	rs2352028
PheGenI	rs2352028
Biobank	rs2352028
1000 genomes	rs2352028
hgdp	rs2352028
ensembl	rs2352028
geneview	rs2352028
scholar	rs2352028
google	rs2352028
pharmgkb	rs2352028
gwascentral	rs2352028
openSNP	rs2352028
23andMe	rs2352028
SNPshot	rs2352028
SNPdbe	rs2352028
MSV3d	rs2352028
GWAS Ctlg	rs2352028

GMAF

0.3636

Max Magnitude

2

?

(C;C) (C;T) (T;T)

28

news increased risk of lung cancer in non smokers. Analysis showed that the presence of this variant significantly increased the risk of a never smoker having lung cancer by 1.46 times (odds ratio 1.46, 95% confidence interval 1.26 to 1.70).

[PMID 20304703 ] Genetic variants and risk of lung cancer in never smokers: a genome-wide association study

[PMID 22236185] GPC5 rs2352028 Polymorphism and Risk of Lung Cancer in Han Chinese

[PMID 24456789] Variants in the 5'-upstream region of GPC5 confer risk of lung cancer in never smokers

[PMID 23297363 ] Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot.