rs3784709
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 1 | Normal risk of developing restless legs syndrome |
| (C;T) | 1.5 | 0.71x risk of developing restless legs syndrome |
| (T;T) | 1.8 | >0.71x risk of developing restless legs syndrome |
| Reference | GRCh38 38.1/141 |
| Chromosome | 15 |
| Position | 67779937 |
| Gene | MAP2K5 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3784709 |
| dbSNP (classic) | rs3784709 |
| ClinGen | rs3784709 |
| ebi | rs3784709 |
| HLI | rs3784709 |
| Exac | rs3784709 |
| Gnomad | rs3784709 |
| Varsome | rs3784709 |
| LitVar | rs3784709 |
| Map | rs3784709 |
| PheGenI | rs3784709 |
| Biobank | rs3784709 |
| 1000 genomes | rs3784709 |
| hgdp | rs3784709 |
| ensembl | rs3784709 |
| geneview | rs3784709 |
| scholar | rs3784709 |
| rs3784709 | |
| pharmgkb | rs3784709 |
| gwascentral | rs3784709 |
| openSNP | rs3784709 |
| 23andMe | rs3784709 |
| SNPshot | rs3784709 |
| SNPdbe | rs3784709 |
| MSV3d | rs3784709 |
| GWAS Ctlg | rs3784709 |
| GMAF | 0.4711 |
| Max Magnitude | 1.8 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs3784709, a SNP located in a region of chromosome 15q, has been linked to a lower frequency of restless legs syndrome, a common sleep disorder, with an overall odds ratio of 0.71 (CI: 0.60-0.83) for the (T) minor allele. [PMID 17637780]
[PMID 19279021
] Replication of restless legs syndrome loci in three European populations.
