| Geno
|
Mag
|
Summary
|
| (A;A)
|
1.5
|
A allele associated with reduced risk of Alzheimer's in Chinese Han population.
|
| (A;C)
|
1.2
|
|
| (C;C)
|
1.1
|
|
Alzheimer's disease associated, based on large 2011 study 10.1038/ng.803
| GWAS snp
|
| PMID
|
[PMID 21460840 ]
|
| Trait
|
|
| Title
|
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
|
| Risk Allele
|
|
| P-val
|
2E-14
|
| Odds Ratio
|
1.1100 [1.09-1.15]
|
[PMID 19734902] Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease.
[PMID 22382309] The prevalence of CD33 and MS4A6A variant in Chinese Han population with Alzheimer's disease.
[PMID 23180304] Genetic risk score predicting accelerated progression from mild cognitive impairment to Alzheimer's disease.
[PMID 23232270] Association of GWAS-linked loci with late-onset Alzheimer's disease in a northern Han Chinese population.
[PMID 25189118] Late-onset Alzheimer's risk variants in memory decline, incident mild cognitive impairment, and Alzheimer's disease
[PMID 26455864] Association of CD33 and MS4A cluster variants with Alzheimer's disease in East Asian Populations
]
