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DDC

From SNPedia
is agene
is mentioned by
Full namedopa decarboxylase (aromatic L-amino acid decarboxylase)
Other namesAADC
EntrezGene1644
PheGenI1644
VariationViewer1644
ClinVarDDC
GeneCardsDDC
dbSNP1644
DiseasesDDC
SADR1644
HugeNav1644
wikipediaDDC
googleDDC
gopubmedDDC
EVSDDC
HEFalMpDDC
MyGene2DDC
23andMeDDC
UniProtP20711
EnsemblENSG00000132437
OMIM107930
# SNPs31
 Max MagnitudeChromosome positionSummary
rs1085307991050,544,015
rs1157546150,479,485
rs11761683150,475,181
rs11974297150,550,562
rs12718541150,482,446
rs137853207050,539,926
rs137853208050,504,025
rs137853209050,495,369
rs137853210050,529,339
rs137853211050,539,958
rs137853212050,499,201
rs1451371050,485,353
rs1451375050,555,014
rs1470750050,508,950
rs201951824050,476,625
rs2044859150,544,864
rs2060762050,461,686
rs2242041050,461,751
rs2329340150,552,531
rs3735273050,529,166
rs375747250,470,285
rs3779084050,501,037
rs3837091050,561,043
rs6264050,544,037
rs6592961050,505,192
rs771317809050,470,140
rs7809234050,542,681
rs7809758050,505,635
rs880028050,502,438
rs921451050,555,587
rs998850050,539,690

catalyzes several decarboxylation reactions:

  • L-DOPA to dopamine - a neurotransmitter
  • 5-HTP to serotonin - also a neurotransmitter
  • tryptophan to tryptamine


per OMIM, Ma et al. (2005) [PMID 15879433] found two different DDC haplotypes associated with nicotine dependence in African Americans and European Americans (with measures of smoking quantity [SQ], heaviness of smoking index [HSI], and the Fagerstrom test for ND [FTND])