Hodgkin lymphoma
From SNPedia
Hodgkin lymphoma is a rare cancer arising from white blood cells. People infected with HIV or Epstein-Barr virus, which causes mononucleosis, have a higher risk of developing Hodgkin lymphoma. Most Hodgkin patients can be cured by treatment with radiation, chemotherapy, or both. Wikipedia
SNPs implicated in susceptibility to Hodgkin lymphoma:
- rs1432295 near the REL gene (risk allele G)
- rs6903608 near the HLA-DRA region may raise the risk of developing EBV-negative Hodgkin lymphoma (risk allele C)
- rs2734986 near the HLA-A gene increases the odds of developing EBV-positive Hodgkin lymphoma (risk allele C)
- rs2019960 in the PVT1 gene (risk allele C)
Some SNPs appear to reduce the risk of Hodgkin lymphoma:
