23andMe blog risk factors contributing to both celiac disease and Crohn’s disease in nearly 10,000 subjects with either disease and more than 10,000 healthy individuals, all of European ancestry. The CC genotypes at both rs10188217 and rs212388 were associated with slightly higher odds of either disease compared to the CT genotype, and the TT genotypes at both SNPs were associated with slightly lower odds.
| GWAS snp
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| PMID
|
[PMID 21298027 ]
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| Trait
|
|
| Title
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A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease
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| Risk Allele
|
C
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| P-val
|
1E-11
|
| Odds Ratio
|
None None
|
[PMID 19068216] Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship.
]
