|?|| (C;C) (C;T) (T;T) ||28|
The C->T (Ser532Leu, rs1059703
) polymorphism of the IRAK1
gene was significantly associated with atherothrombotic cerebral infarction in a study of 3,400+ Japanese adults.[PMID 18566305
[PMID 20500689] The Role of microRNA-146a (miR-146a) and its Target IL-1R-Associated Kinase (IRAK1) in Psoriatic Arthritis Susceptibility
[PMID 20870441] A polymorphism in the 3'-UTR of interleukin-1 receptor-associated kinase (IRAK1), a target gene of miR-146a, is associated with rheumatoid arthritis susceptibility
[PMID 17382928] The association between innate immunity gene (IRAK1) and C-reactive protein in the Diabetes Heart Study.
[PMID 18987746] Association of interacting genes in the toll-like receptor signaling pathway and the antibody response to pertussis vaccination.
[PMID 19288030] Association of genetic variants with chronic kidney disease in Japanese individuals with type 2 diabetes mellitus.
[PMID 19505919] Toll-like receptor signaling pathway variants and prostate cancer mortality.
[PMID 20463618] Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.
[PMID 23233309] An activity-enhancing variant of IRAK1 and an MECP2-IRAK1 haplotype associating with increased susceptibility to rheumatoid arthritis
[PMID 23867959] Toll-like receptor genetic variants are associated with Gram-negative infections in VLBW infants
[PMID 25458699] Variants in IRAK1-MECP2 region confer susceptibility to autoimmune thyroid diseases