[PMID 19088850] rs10830962, rs4753426, and rs10830963 were significantly associated with higher fasting plasma glucose concentrations and reduced OGTT- and IVGTT-induced insulin release. rs3781638 displayed significant association with lower fasting plasma glucose levels and increased OGTT-induced insulin release
[PMID 22233651] A Genome-Wide Association Study of Gestational Diabetes Mellitus in Korean Women
GWAS snp
|
PMID
|
[PMID 21909109]
|
Trait
|
|
Title
|
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
|
Risk Allele
|
C
|
P-val
|
1E-16
|
Odds Ratio
|
0.0445 [0.034-0.055] mg/dL increase
|
GWAS snp
|
PMID
|
[PMID 22399527]
|
Trait
|
|
Title
|
Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
|
Risk Allele
|
G
|
P-val
|
5E-16
|
Odds Ratio
|
0.1200 None
|
[PMID 19184136] Examination of association of genes in the serotonin system to autism.
[PMID 20959387] Association of rs10830963 and rs10830962 SNPs in the melatonin receptor (MTNR1B) gene among Han Chinese women with polycystic ovary syndrome.
GWAS snp
|
PMID
|
[PMID 23575436]
|
Trait
|
Glycemic traits
|
Title
|
New susceptibility loci in MYL2, C12orf51 and OAS1 associated with 1-h plasma glucose as predisposing risk factors for type 2 diabetes in the Korean population.
|
Risk Allele
|
C
|
P-val
|
5E-13
|
Odds Ratio
|
.04 [0.029-0.053] mmol-1 increase
|
[PMID 24157813] Association between Genetic Variations in MTNR1A and MTNR1B Genes and Gestational Diabetes Mellitus in Han Chinese Women
[PMID 23611530] Genetics of melatonin receptor type 2 is associated with left ventricular function in hypertensive patients treated according to guidelines.