rs11024102
| Orientation | plus |
| Stabilized | plus |
| Make rs11024102(C;C) |
| Make rs11024102(C;T) |
| Make rs11024102(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 11 |
| Position | 16987058 |
| Gene | PLEKHA7 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs11024102 |
| dbSNP (classic) | rs11024102 |
| ClinGen | rs11024102 |
| ebi | rs11024102 |
| HLI | rs11024102 |
| Exac | rs11024102 |
| Gnomad | rs11024102 |
| Varsome | rs11024102 |
| LitVar | rs11024102 |
| Map | rs11024102 |
| PheGenI | rs11024102 |
| Biobank | rs11024102 |
| 1000 genomes | rs11024102 |
| hgdp | rs11024102 |
| ensembl | rs11024102 |
| geneview | rs11024102 |
| scholar | rs11024102 |
| rs11024102 | |
| pharmgkb | rs11024102 |
| gwascentral | rs11024102 |
| openSNP | rs11024102 |
| 23andMe | rs11024102 |
| SNPshot | rs11024102 |
| SNPdbe | rs11024102 |
| MSV3d | rs11024102 |
| GWAS Ctlg | rs11024102 |
| GMAF | 0.2567 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
| GWAS snp | |
|---|---|
| PMID | [PMID 22922875 ]
|
| Trait | Glaucoma (primary open-angle) |
| Title | Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma. |
| Risk Allele | G |
| P-val | 5E-12 |
| Odds Ratio | 1.22 [NR] |
[PMID 23847314] Association study in a South Indian population supports rs1015213 as a risk factor for primary angle closure
[PMID 23505305] Genotype-phenotype analysis of SNPs associated with primary angle closure glaucoma (rs1015213, rs3753841 and rs11024102) and ocular biometry in the EPIC-Norfolk Eye Study.
[PMID 24854855] Extended association study of PLEKHA7 and COL11A1 with primary angle closure glaucoma in a Han Chinese population
[PMID 26268645] [Statistical model analysis of primary angle closure glaucoma associated genes and SNP]
[PMID 29016860] Primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 encodes a novel Rac1/Cdc42 GAP that modulates cell migration and blood-aqueous barrier function.
[PMID 32682838] Evaluation of primary angle closure glaucoma susceptibility loci for estimating angle closure disease severity.
