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From SNPedia

[PMID 23517743] The protease activated receptor 1 gene variation IVSn -14A>T is associated with distant metastasis and cancer-specific survival in renal cell carcinoma [PMID 20585578OA-icon.png] The interaction between coagulation factor 2 receptor and interleukin 6 haplotypes increases the risk of myocardial infarction in men.

[PMID 26535635] Role of proteinase-activated receptor-1 gene polymorphisms in susceptibility to chronic obstructive pulmonary disease