23andMe blog each rs1183910(T) lowered CRP by 13.8% also associated with higher total cholesterol, LDL choesterol and HDL cholesterol.
[PMID 19567438] Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease
GWAS snp
|
PMID
|
[PMID 21300955]
|
Trait
|
|
Title
|
Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels
|
Risk Allele
|
G
|
P-val
|
2E-124
|
Odds Ratio
|
0.1490 [0.14-0.16] unit increase
|
[PMID 18439552] Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.
GWAS snp
|
PMID
|
[PMID 23844046]
|
Trait
|
C-reactive protein
|
Title
|
Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?
|
Risk Allele
|
G
|
P-val
|
4E-12
|
Odds Ratio
|
.05 [NR] unit increase
|