rs1376251
| Orientation | plus |
| Stabilized | plus |
| Make rs1376251(C;C) |
| Make rs1376251(C;T) |
| Make rs1376251(T;T) |
| Reference | GRCh37.p2 37.2/134 |
| Chromosome | 12 |
| Position | 10986253 |
| Gene | PRH1, PRH1-PRR4, PRH1-TAS2R14, TAS2R50 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1376251 |
| dbSNP (classic) | rs1376251 |
| ClinGen | rs1376251 |
| ebi | rs1376251 |
| HLI | rs1376251 |
| Exac | rs1376251 |
| Gnomad | rs1376251 |
| Varsome | rs1376251 |
| LitVar | rs1376251 |
| Map | rs1376251 |
| PheGenI | rs1376251 |
| Biobank | rs1376251 |
| 1000 genomes | rs1376251 |
| hgdp | rs1376251 |
| ensembl | rs1376251 |
| geneview | rs1376251 |
| scholar | rs1376251 |
| rs1376251 | |
| pharmgkb | rs1376251 |
| gwascentral | rs1376251 |
| openSNP | rs1376251 |
| 23andMe | rs1376251 |
| SNPshot | rs1376251 |
| SNPdbe | rs1376251 |
| MSV3d | rs1376251 |
| GWAS Ctlg | rs1376251 |
| GMAF | 0.3981 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs1376251 increases susceptibility to Myocardial Infarction 1.23 times for heterozygotes (CT) and 1.58 times for homozygotes (CC) [PMID 16175505
]
An independent study of 3657 patients with myocardial infarction (885 women and 2772 men) and 1211 control individuals (598 women and 613 men) did not observe any correlation to this SNP.[PMID 19709766]
[PMID 22192511] KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly
[PMID 22856164] [Evaluation of association between 9 genetic polymorphism and myocardial infarction in the Siberian population]
[PMID 18599554] Replication study of 10 genetic polymorphisms associated with coronary heart disease in a specific high-risk population with familial hypercholesterolemia.
[PMID 19092995] Bitter taste receptors influence glucose homeostasis.
[PMID 19924713] Use of longitudinal data in genetic studies in the genome-wide association studies era: summary of Group 14.
[PMID 20017983] Evaluation of population impact of candidate polymorphisms for coronary heart disease in the Framingham Heart Study Offspring Cohort.
[PMID 24083639] Variations in Bitter-Taste Receptor Genes, Dietary Intake, and Colorectal Adenoma Risk
[PMID 32811377] Extreme Phenotype Approach Suggests Taste Transduction Pathway for Carotid Plaque in a Multi-Ethnic Cohort.
