| GWAS snp
|
| PMID
|
[PMID 18587394 ]
|
| Trait
|
Crohn's disease
|
| Title
|
Genome-wide assocation defines more than 30 distinct susceptibility loci for Crohn's disease
|
| Risk Allele
|
A
|
| P-val
|
5.0000000000000001E-9
|
| Odds Ratio
|
1.12 [NR]
|
| OMIM | 612380 |
| Desc | INFLAMMATORY BOWEL DISEASE 22; IBD22 |
| Variant | |
| Related | also |
[PMID 21072187] Evidence for Significant Overlap between Common Risk Variants for Crohn's Disease and Ankylosing Spondylitis
| GWAS snp
|
| PMID
|
[PMID 21297633]
|
| Trait
|
|
| Title
|
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
|
| Risk Allele
|
A
|
| P-val
|
5E-11
|
| Odds Ratio
|
1.1500 [1.10-1.19]
|
[PMID 21752155] Genetic susceptibility to inflammation and colonic transit in lower functional gastrointestinal disorders: preliminary analysis
| GWAS snp
|
| PMID
|
[PMID 21829393]
|
| Trait
|
|
| Title
|
Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.
|
| Risk Allele
|
A
|
| P-val
|
0.000002
|
| Odds Ratio
|
1.1000 [NR]
|
[PMID 22365150] Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12
[PMID 19068216] Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship.
[PMID 19264973] Assessing the reproducibility of asthma candidate gene associations, using genome-wide data.
[PMID 19474294] Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.
[PMID 19732864] Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease.
[PMID 20369022] Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations.
[PMID 21304977] An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.
| GWAS snp
|
| PMID
|
[PMID 21102463]
|
| Trait
|
Crohn's disease
|
| Title
|
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
| Risk Allele
|
A
|
| P-val
|
2E-9
|
| Odds Ratio
|
1.14 [1.09-1.19]
|
[PMID 22694930] Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases.
[PMID 22986918] Association among ORMDL3 gene expression, 17q21 polymorphism and response to treatment with inhaled corticosteroids in children with asthma.
[PMID 29510406] Polymorphisms of IKZF3 Gene and Autoimmune Thyroid Diseases: Associated with Graves' Disease but Not with Hashimoto's Thyroiditis.
]
