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rs2875907

From SNPedia

Orientationplus
Stabilizedplus
Make rs2875907(A;A)
Make rs2875907(A;G)
Make rs2875907(G;G)
ReferenceGRCh38.p7 38.3/150
Chromosome3
Position85469430
GeneCADM2
is asnp
is mentioned by
dbSNPrs2875907
dbSNP (classic)rs2875907
ClinGenrs2875907
ebirs2875907
HLIrs2875907
Exacrs2875907
Gnomadrs2875907
Varsomers2875907
LitVarrs2875907
Maprs2875907
PheGenIrs2875907
Biobankrs2875907
1000 genomesrs2875907
hgdprs2875907
ensemblrs2875907
geneviewrs2875907
scholarrs2875907
googlers2875907
pharmgkbrs2875907
gwascentralrs2875907
openSNPrs2875907
23andMers2875907
SNPshotrs2875907
SNPdbers2875907
MSV3drs2875907
GWAS Ctlgrs2875907
Max Magnitude0
? (A;A) (A;G) (G;G) 28


This SNP in the CADM2 gene was found to contribute to life time cannabis use. (p<e-16), beta= 0.070).

Cannabis use is positively associated with a range of other behaviors including alcohol dependence, depression, ADHD, Schizophrenia, bipolar, autism, risk taking and educational attainment and negatively with conscientiousness and subjective well being. This study with 185,000 ever cannabis users discovered 10% of the variance in lifetime cannabis use.

(Genome-wide association analysis of lifetime cannabis use (N=184,765) identifies new risk loci, genetic overlap with mental health, and a causal influence of schizophrenia on cannabis use Biorxiv)

The significant SNPs were (rsID, gene; A1, A2, A1-Freq):