Note: the 2016 paper discussing a potential algorithm for Alzheimer's risk based on ApoE promoter polymorphisms, [PMID 27193889], is considered too preliminary (and based on too few patients) to add to SNPedia in any detail. [PMID 19282863] Association of candidate gene polymorphisms with chronic kidney disease in Japanese individuals with hypertension [PMID 19384966] Age-related macular degeneration and functional promoter and coding variants of the apolipoprotein E gene [PMID 19808960] Apolipoprotein E/C1 Locus Variants Modify Renal Cell Carcinoma Risk [PMID 21263195] An APOE Haplotype Associated with Decreased ?4 Expression Increases the Risk of Late Onset Alzheimer's Disease [PMID 21266206] Association of apolipoprotein E promoter polymorphisms with bone structural traits is modified by dietary saturated fat intake - The Cardiovascular Risk in Young Finns Study [PMID 22028770] APOE Genotype-Function Relationship: Evidence of -491 A/T Promoter Polymorphism Modifying Transcription Control but Not Type 2 Diabetes Risk [PMID 16617143] Algorithm for automatic genotype calling of single nucleotide polymorphisms using the full course of TaqMan real-time data. [PMID 17356695] Variation in GYS1 interacts with exercise and gender to predict cardiovascular mortality. [PMID 17357073] Genetic analysis of 103 candidate genes for coronary artery disease and associated phenotypes in a founder population reveals a new association between endothelin-1 and high-density lipoprotein cholesterol. [PMID 17672902] Subarachnoid hemorrhage: tests of association with apolipoprotein E and elastin genes. [PMID 18161859] Does APOE explain the linkage of Alzheimer's disease to chromosome 19q13? [PMID 18254975] Physiogenomic comparison of human fat loss in response to diets restrictive of carbohydrate or fat. [PMID 18280754] Cholesterol-related genetic risk scores are associated with hypometabolism in Alzheimer's-affected brain regions. [PMID 18813964] Alzheimer's disease risk variants show association with cerebrospinal fluid amyloid beta. [PMID 18823527] A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. [PMID 19118814] Genome-wide association study implicates a chromosome 12 risk locus for late-onset Alzheimer disease. [PMID 19327864] SNPit: a federated data integration system for the purpose of functional SNP annotation. [PMID 19406964] Association of genetic variants with chronic kidney disease in Japanese individuals. [PMID 19408013] Strategies and issues in the detection of pathway enrichment in genome-wide association studies. [PMID 19541455] Apolipoprotein-E gene variants associated with cardiovascular risk factors in antipsychotic recipients. [PMID 19668339] Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease. [PMID 19734902] Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. [PMID 20396431] Genotyping sleep disorders patients. [PMID 20467002] Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls. [PMID 20723945] The APOE -219G/T and +113G/C polymorphisms affect insulin resistance among Turks. [PMID 21283811] Associations between APOE variants and metabolic traits and the impact of psychological stress. [PMID 21882290] Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies. [PMID 22430674] Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease. [PMID 23021345] Gene-diet interactions on plasma lipid levels in the Inuit population. [PMID 23193196] Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis. [PMID 25085564] Influence of multiple
|Disease||Myocardial infarction Coronary artery disease|
|CLNDBN||Myocardial infarction Coronary artery disease, severe, susceptibility to|
|CLNSRC||OMIM Allelic Variant|
[PMID 26405973] Gene environment interaction of GALNT2 and APOE gene with hypertension in the Chinese Han Population
[PMID 28346566] Gene- Gene Interaction between PPARG and APOE Gene on Late-Onset Alzheimer's Disease: A Case- Control Study in Chinese Han Population.
[PMID 30706571] A candidate gene study of risk for dementia in older, post-menopausal women: Results from the Women's Health Initiative Memory Study.
[PMID 31426376] APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer's Disease Risk in a Multiracial Sample.
[PMID 32682842] APOE rs405509 polymorphism and Parkinson's disease risk in the Chinese population.