rs4147929
From SNPedia
Orientation | plus |
Stabilized | plus |
Make rs4147929(A;A) |
Make rs4147929(A;G) |
Make rs4147929(G;G) |
Reference | GRCh38 38.1/141 |
Chromosome | 19 |
Position | 1063444 |
Gene | ABCA7 |
is a | snp |
is | mentioned by |
dbSNP | rs4147929 |
dbSNP (classic) | rs4147929 |
ClinGen | rs4147929 |
ebi | rs4147929 |
HLI | rs4147929 |
Exac | rs4147929 |
Gnomad | rs4147929 |
Varsome | rs4147929 |
LitVar | rs4147929 |
Map | rs4147929 |
PheGenI | rs4147929 |
Biobank | rs4147929 |
1000 genomes | rs4147929 |
hgdp | rs4147929 |
ensembl | rs4147929 |
geneview | rs4147929 |
scholar | rs4147929 |
rs4147929 | |
pharmgkb | rs4147929 |
gwascentral | rs4147929 |
openSNP | rs4147929 |
23andMe | rs4147929 |
SNPshot | rs4147929 |
SNPdbe | rs4147929 |
MSV3d | rs4147929 |
GWAS Ctlg | rs4147929 |
Max Magnitude | 0 |
rs4147929 is a SNP in the ATP-binding cassette, sub-family A (ABC1), member 7 ABCA7 gene.
rs4147929 has been reported in a large study (IGAP) to be associated with late onset Alzheimer's disease. The risk allele (oriented to the dbSNP entry) is (A); the odds ratio associated with heterozygotes is 1.15 (CI 1.11-1.19), [PMID 24443964]
GWAS snp | |
---|---|
PMID | [PMID 24162737] |
Trait | Alzheimer's disease (late onset) |
Title | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. |
Risk Allele | A |
P-val | 1E-15 |
Odds Ratio | 1.15 [1.11-1.19] |
[PMID 26141617] Mutations in ABCA7 in a Belgian cohort of Alzheimer's disease patients: a targeted resequencing study
[PMID 29872490] Genome-wide significant risk factors on chromosome 19 and the APOE locus.