rs4607103

Orientation

plus

Stabilized

plus

Make rs4607103(C;C)

Make rs4607103(C;T)

Make rs4607103(T;T)

Reference

GRCh38 38.1/141

Chromosome

3

Position

64726228

Gene	ADAMTS9-AS2

is a	snp
is	mentioned by
dbSNP	rs4607103
dbSNP (classic)	rs4607103
ClinGen	rs4607103
ebi	rs4607103
HLI	rs4607103
Exac	rs4607103
Gnomad	rs4607103
Varsome	rs4607103
LitVar	rs4607103
Map	rs4607103
PheGenI	rs4607103
Biobank	rs4607103
1000 genomes	rs4607103
hgdp	rs4607103
ensembl	rs4607103
geneview	rs4607103
scholar	rs4607103
google	rs4607103
pharmgkb	rs4607103
gwascentral	rs4607103
openSNP	rs4607103
23andMe	rs4607103
SNPshot	rs4607103
SNPdbe	rs4607103
MSV3d	rs4607103
GWAS Ctlg	rs4607103

GMAF

0.303

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

GWAS
SNP	rs4607103
PubMedID	[PMID 18372903]
Condition	Type 2 diabetes
Gene	ADAMTS9
Risk Allele	C
pValue	1.00E-008
OR	1.09
95% CI	1.06-1.12

[PMID 19455301] Replication study for the association of new meta-analysis-derived risk loci with susceptibility to type 2 diabetes in 6,244 Japanese individuals

[PMID 19789630] Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study

[PMID 18567820] Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.

[PMID 18591388] Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk.

[PMID 18694974] Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study.

[PMID 18714373] Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes.

[PMID 18782870] Clinical review: the genetics of type 2 diabetes: a realistic appraisal in 2008.

[PMID 18852197] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.

[PMID 19020323] Genotype score in addition to common risk factors for prediction of type 2 diabetes.

[PMID 19056611] Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.

[PMID 19096518] Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.

[PMID 19207020] Meta-analysis in genome-wide association studies.

[PMID 19323962] Genome-wide association studies in type 2 diabetes.

[PMID 19324937] Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults.

[PMID 19341491] Genome-based prediction of common diseases: methodological considerations for future research.

[PMID 19401414] Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.

[PMID 19460916] Genetic architecture of type 2 diabetes: recent progress and clinical implications.

[PMID 19502414] Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.

[PMID 19526209] Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?

[PMID 19602701] Underlying genetic models of inheritance in established type 2 diabetes associations.

[PMID 19639606] Correcting "winner's curse" in odds ratios from genomewide association findings for major complex human diseases.

[PMID 19741467] Association of common type 2 diabetes risk gene variants and posttransplantation diabetes mellitus in renal allograft recipients in Korea.

[PMID 19862325] PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population.

[PMID 19956539] How many genetic variants remain to be discovered?

[PMID 20017978] Influence of control selection in genome-wide association studies: the example of diabetes in the Framingham Heart Study.

[PMID 20018066] Epistatic interactions of CDKN2B-TCF7L2 for risk of type 2 diabetes and of CDKN2B-JAZF1 for triglyceride/high-density lipoprotein ratio longitudinal change: evidence from the Framingham Heart Study.

[PMID 20043853] Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus.

[PMID 20075150] Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study.

[PMID 20144327] A genomics study of type 2 diabetes mellitus in U.S. Air Force personnel.

[PMID 20161779] Investigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort.

[PMID 20712903] Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study.

[PMID 21278902] Genetic risk profiling for prediction of type 2 diabetes.

[PMID 22377712] Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography.

[PMID 23161442] PPARG2 Pro12Ala and ADAMTS9 rs4607103 as "insulin resistance loci" and "insulin secretion loci" in Italian individuals. The GENFIEV study and the Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) 4.

[PMID 23298195] Association study of genetic variants of 17 diabetes-related genes/loci and cardiovascular risk and diabetic nephropathy in the Chinese She population.

[PMID 23462794] Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets.