rs4788102
Orientation | plus |
Stabilized | plus |
Make rs4788102(A;A) |
Make rs4788102(A;G) |
Make rs4788102(G;G) |
Reference | GRCh38 38.1/141 |
Chromosome | 16 |
Position | 28862077 |
Gene | SH2B1 |
is a | snp |
is | mentioned by |
dbSNP | rs4788102 |
dbSNP (classic) | rs4788102 |
ClinGen | rs4788102 |
ebi | rs4788102 |
HLI | rs4788102 |
Exac | rs4788102 |
Gnomad | rs4788102 |
Varsome | rs4788102 |
LitVar | rs4788102 |
Map | rs4788102 |
PheGenI | rs4788102 |
Biobank | rs4788102 |
1000 genomes | rs4788102 |
hgdp | rs4788102 |
ensembl | rs4788102 |
geneview | rs4788102 |
scholar | rs4788102 |
rs4788102 | |
pharmgkb | rs4788102 |
gwascentral | rs4788102 |
openSNP | rs4788102 |
23andMe | rs4788102 |
SNPshot | rs4788102 |
SNPdbe | rs4788102 |
MSV3d | rs4788102 |
GWAS Ctlg | rs4788102 |
GMAF | 0.2649 |
Max Magnitude | 0 |
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
association with obesity [PMID 19079260]
[PMID 21907990] The SH2B1 obesity locus is associated with myocardial infarction in diabetic patients and with NO synthase activity in endothelial cells
[PMID 17228025] The SH2B gene is associated with serum leptin and body fat in normal female twins.
[PMID 19478790] The role of obesity-associated loci identified in genome-wide association studies in the determination of pediatric BMI.
[PMID 23054017] The joint effect of cigarette smoking and polymorphisms on LRP5, LEPR, near MC4R and SH2B1 genes on metabolic syndrome susceptibility in Taiwan
[PMID 23424664] Study of 11 BMI-associated loci identified in GWAS for associations with central obesity in the Chinese children
[PMID 24103803] The SH2B1 obesity locus and abnormal glucose homeostasis: Lack of evidence for association from a meta-analysis in individuals of European ancestry
[PMID 24269186] An obesity genetic risk score is associated with metabolic syndrome in Chinese children
[PMID 23121087] Sex-dependent associations of genetic variants identified by GWAS with indices of adiposity and obesity risk in a Chinese children population.
[PMID 25492288] [Impact of obesity-related gene polymorphism on risk of obesity and metabolic disorder in childhood]