rs548234

Orientation

plus

Stabilized

plus

Make rs548234(C;C)

Make rs548234(C;T)

Make rs548234(T;T)

Reference

GRCh38 38.1/141

Chromosome

6

Position

106120159

Gene	LOC100287304

is a	snp
is	mentioned by
dbSNP	rs548234
dbSNP (classic)	rs548234
ClinGen	rs548234
ebi	rs548234
HLI	rs548234
Exac	rs548234
Gnomad	rs548234
Varsome	rs548234
LitVar	rs548234
Map	rs548234
PheGenI	rs548234
Biobank	rs548234
1000 genomes	rs548234
hgdp	rs548234
ensembl	rs548234
geneview	rs548234
scholar	rs548234
google	rs548234
pharmgkb	rs548234
gwascentral	rs548234
openSNP	rs548234
23andMe	rs548234
SNPshot	rs548234
SNPdbe	rs548234
MSV3d	rs548234
GWAS Ctlg	rs548234

GMAF

0.23

Max Magnitude

0

?	(C;C) (C;T) (T;T)	28

GWAS snp
PMID	[PMID 19838193]
Trait	Systemic lupus erythematosus
Title	Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus
Risk Allele	G
P-val	5E-12
Odds Ratio	1.25 [1.17-1.33]

OMIM	180300
Desc
Variant
Related	also

[PMID 21622776] Genetic association of PRDM1-ATG5 intergenic region and autophagy with systemic lupus erythematosus in a Chinese population

[PMID 22040493] Rs548234 polymorphism at PRDM1-ATG5 region susceptible to rheumatoid arthritis in Caucasians is not associated with rheumatoid arthritis in Chinese Han population

[PMID 19898481] Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk.

[PMID 22328738] Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.

[PMID 26420661] Gene-gene interaction of ATG5, ATG7, BLK and BANK1 in systemic lupus erythematosus

[PMID 28097234] Kruppel-like factor4 regulates PRDM1 expression through binding to an autoimmune risk allele.