rs6474413 increases susceptibility to Substance dependence, Nicotine 1.35 times for carriers of the T allele [PMID 17135278
]
[PMID 19482438] Association of genes coding for the alpha-4, alpha-5, beta-2 and beta-3 subunits of nicotinic receptors with cigarette smoking and nicotine dependence
[PMID 17158188
] Novel genes identified in a high-density genome wide association study for nicotine dependence.
[PMID 18565990
] Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence.
[PMID 18571741
] Genetic variability in nicotinic acetylcholine receptors and nicotine addiction: converging evidence from human and animal research.
[PMID 18704094
] Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample.
[PMID 19029397
] Nicotinic receptor gene variants influence susceptibility to heavy smoking.
[PMID 19184766
] A testable prognostic model of nicotine dependence.