rs6840978

Orientation

plus

Stabilized

plus

Make rs6840978(C;C)

Make rs6840978(C;T)

Make rs6840978(T;T)

Reference

GRCh38 38.1/141

Chromosome

4

Position

122633552

Gene

IL21-AS1

is a	snp
is	mentioned by
dbSNP	rs6840978
dbSNP (classic)	rs6840978
ClinGen	rs6840978
ebi	rs6840978
HLI	rs6840978
Exac	rs6840978
Gnomad	rs6840978
Varsome	rs6840978
LitVar	rs6840978
Map	rs6840978
PheGenI	rs6840978
Biobank	rs6840978
1000 genomes	rs6840978
hgdp	rs6840978
ensembl	rs6840978
geneview	rs6840978
scholar	rs6840978
google	rs6840978
pharmgkb	rs6840978
gwascentral	rs6840978
openSNP	rs6840978
23andMe	rs6840978
SNPshot	rs6840978
SNPdbe	rs6840978
MSV3d	rs6840978
GWAS Ctlg	rs6840978

GMAF

0.14

Max Magnitude

0

?

(C;C) (C;T) (T;T)

28

[PMID 19455118] Novel Genetic Risk Markers for Ulcerative Colitis in the IL2/IL21 Region Are in Epistasis With IL23R and Suggest a Common Genetic Background for Ulcerative Colitis and Celiac Disease

[PMID 19201773 ] Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis

[PMID 20184734 ] The 4q27 locus and familial prostate cancer risk

[PMID 17558408 ] A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21.

[PMID 18311140 ] Newly identified genetic risk variants for celiac disease related to the immune response.

[PMID 18369459 ] A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.

[PMID 19546505 ] IL-21 drives secondary autoimmunity in patients with multiple sclerosis, following therapeutic lymphocyte depletion with alemtuzumab (Campath-1H).

[PMID 20553587 ] Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.

[PMID 21304239] Analysis of IL2/IL21 gene variants in cholestatic liver diseases reveals an association with primary sclerosing cholangitis.

[PMID 26535636] Association between IL2/IL21 and SH2B3 polymorphisms and risk of celiac disease: a meta-analysis