rs7310409
Orientation | plus |
Stabilized | plus |
Make rs7310409(A;A) |
Make rs7310409(A;G) |
Make rs7310409(G;G) |
Reference | GRCh38 38.1/141 |
Chromosome | 12 |
Position | 120987058 |
Gene | HNF1A |
is a | snp |
is | mentioned by |
dbSNP | rs7310409 |
dbSNP (classic) | rs7310409 |
ClinGen | rs7310409 |
ebi | rs7310409 |
HLI | rs7310409 |
Exac | rs7310409 |
Gnomad | rs7310409 |
Varsome | rs7310409 |
LitVar | rs7310409 |
Map | rs7310409 |
PheGenI | rs7310409 |
Biobank | rs7310409 |
1000 genomes | rs7310409 |
hgdp | rs7310409 |
ensembl | rs7310409 |
geneview | rs7310409 |
scholar | rs7310409 |
rs7310409 | |
pharmgkb | rs7310409 |
gwascentral | rs7310409 |
openSNP | rs7310409 |
23andMe | rs7310409 |
SNPshot | rs7310409 |
SNPdbe | rs7310409 |
MSV3d | rs7310409 |
GWAS Ctlg | rs7310409 |
GMAF | 0.3935 |
Max Magnitude | 0 |
A study of 12,854 Japanese subjects replicated the finding of an association between rs7310409 and serum CRP levels.[PMID 21196492]
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
GWAS | |
---|---|
SNP | rs7310409 |
PubMedID | [PMID 18439548] |
Condition | C-reactive protein |
Gene | HNF1A |
Risk Allele | A |
pValue | 7.00E-017 |
OR | 0.15 |
95% CI | NR) mg/dl decreas |
GWAS snp | |
---|---|
PMID | [PMID 21196492] |
Trait | |
Title | Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus |
Risk Allele | G |
P-val | 3E-8 |
Odds Ratio | 0.0700 [0.04-0.10] unit increase |
GWAS snp | |
---|---|
PMID | [PMID 22001757] |
Trait | |
Title | Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. |
Risk Allele | G |
P-val | 7E-45 |
Odds Ratio | 6.8000 None |
[PMID 18439552] Polymorphisms of the HNF1A gene encoding hepatocyte nuclear factor-1 alpha are associated with C-reactive protein.
[PMID 18852197] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
[PMID 19197348] Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae.
[PMID 19474294] Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.
[PMID 20031577] Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.
[PMID 21195701] Effect of obesity on the association between common variations in the HNF1A gene region and C-reactive protein level in Taiwanese.
[PMID 21498636] Genome-wide "pleiotropy scan" identifies HNF1A region as a novel pancreatic cancer susceptibility locus.
[PMID 21647738] Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment.
[PMID 22569176] MALDI-TOF mass spectrometry screening of cholelithiasis risk markers in the gene of HNF1alpha.
[PMID 23092954] SHAVE: shrinkage estimator measured for multiple visits increases power in GWAS of quantitative traits.
[PMID 23183503] Variants within HNF1alpha and ANGPTL4 genes and acute coronary syndrome in Czech population. The GENDEMIP study.
[PMID 24671014] Genetic risk assessment for cardiovascular disease with seven genes associated with plasma C-reactive protein concentrations in Asian populations