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rs806377

From SNPedia

Orientationplus
Stabilizedplus
Make rs806377(C;C)
Make rs806377(C;T)
Make rs806377(T;T)
ReferenceGRCh38 38.1/141
Chromosome6
Position88149004
GeneCNR1
is asnp
is mentioned by
dbSNPrs806377
dbSNP (classic)rs806377
ClinGenrs806377
ebirs806377
HLIrs806377
Exacrs806377
Gnomadrs806377
Varsomers806377
LitVarrs806377
Maprs806377
PheGenIrs806377
Biobankrs806377
1000 genomesrs806377
hgdprs806377
ensemblrs806377
geneviewrs806377
scholarrs806377
googlers806377
pharmgkbrs806377
gwascentralrs806377
openSNPrs806377
23andMers806377
SNPshotrs806377
SNPdbers806377
MSV3drs806377
GWAS Ctlgrs806377
GMAF0.4775
Max Magnitude0
? (C;C) (C;T) (T;T) 28


rs806377(C) together with rs6454674(G) make up a haplotype associated (p=0.008) with higher risk of ADHD. In addition, the haplotype was more associated (p=0.03) with ADHD in males than in females with the risk haplotype. [PMID 18213623OA-icon.png]

[PMID 16917946OA-icon.png] Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents.

[PMID 19016476OA-icon.png] Evidence for association between polymorphisms in the cannabinoid receptor 1 (CNR1) gene and cannabis dependence.

[PMID 19052543OA-icon.png] Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample.

[PMID 19335651OA-icon.png] Candidate genes for cannabis use disorders: findings, challenges and directions.

[PMID 19443135OA-icon.png] The association between cannabinoid receptor 1 gene (CNR1) and cannabis dependence symptoms in adolescents and young adults.

[PMID 21714860OA-icon.png] Variation in the human cannabinoid receptor CNR1 gene modulates gaze duration for happy faces. (C;C) associated with the highest striatal response is also associated with the longest gaze duration for happy faces.


[PMID 23407780] Screening genetic variability at the CNR1 gene in both major depression etiology and clinical response to citalopram treatment.


[PMID 23422373] CNR1 gene and risk of the metabolic syndrome in patients with schizophrenia.