rs9376092

Orientation

plus

Stabilized

plus

Make rs9376092(A;A)

Make rs9376092(A;C)

Make rs9376092(C;C)

Reference

GRCh38 38.1/141

Chromosome

6

Position

135106006

Gene	LOC105378010

is a	snp
is	mentioned by
dbSNP	rs9376092
dbSNP (classic)	rs9376092
ClinGen	rs9376092
ebi	rs9376092
HLI	rs9376092
Exac	rs9376092
Gnomad	rs9376092
Varsome	rs9376092
LitVar	rs9376092
Map	rs9376092
PheGenI	rs9376092
Biobank	rs9376092
1000 genomes	rs9376092
hgdp	rs9376092
ensembl	rs9376092
geneview	rs9376092
scholar	rs9376092
google	rs9376092
pharmgkb	rs9376092
gwascentral	rs9376092
openSNP	rs9376092
23andMe	rs9376092
SNPshot	rs9376092
SNPdbe	rs9376092
MSV3d	rs9376092
GWAS Ctlg	rs9376092

GMAF

0.2548

Max Magnitude

0

?	(A;A) (A;C) (C;C)	28

GWAS snp
PMID	[PMID 19924444]
Trait	Beta thalassemia/hemoglobin E disease
Title	A genome-wide association identified the common genetic variants influence disease severity in beta(0)-thalassemia/hemoglobin E
Risk Allele
P-val	2E-11
Odds Ratio	2.91 [2.12-3.99]

GWAS snp
PMID	[PMID 20183929]
Trait	Beta thalassemia/hemoglobin E disease
Title	A genome-wide association identified the common genetic variants influence disease severity in beta0-thalassemia/hemoglobin E.
Risk Allele
P-val	2E-11
Odds Ratio	2.9100 [2.12-3.99]

[PMID 17592125] Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults.

[PMID 19148297] Genetic variation on chromosome 6 influences F cell levels in healthy individuals of African descent and HbF levels in sickle cell patients.

[PMID 20401335] Sickle Cell Disease in the Post Genomic Era: A Monogenic Disease with a Polygenic Phenotype.