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Sciatica is a set of symptoms involving pain resulting from irritation or compression of the sciatic nerve or nerves leading to it.[Wikipedia]
A haplotype of the IL6 gene appears to be overrepresented in sciatica patients.[PMID 15733644, PMID 18321738]. The haplotype consists of SNPs rs1800797-rs1800796- rs1800795-rs13306435.