Skin is the largest organ of the body. It has three layers, epidermis, dermis and hypodermis. The outermost layer of the skin is the epidermis, the layer beneath the epidermis is the dermis,and the deeper subcutaneous tissues is hypodermis. For exxample the skin color is created by special cells, melanocytes, located in epidermis, that produce the pigment melanin.
[PMID 29895819] Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations.
[PMID 28502801] Genome-Wide Association Shows that Pigmentation Genes Play a Role in Skin Aging.
[PMID 25705849] A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots.
[PMID 24076068] Functional characterisation of a SNP in the ABCC11 allele - effects on axillary skin metabolism, odour generation and associated behaviours.
[PMID 23325016] Dependence of deodorant usage on ABCC11 genotype: scope for personalized genetics in personal hygiene.
Skin cancer and melanoma
Eyelids and eyebrows
- rs1415425 - double-edged eyelids
- rs12570134 - double-edged eyelids
- rs17833789 - freckles
- rs10810635 - freckles
- rs6542772 - excessive hairiness
- rs6059655 - facial pigmented spots
- rs12203592 - facial pigmented spots
- rs62543565 - facial pigmented spots
Sweating and body odor