rs11881222
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 0 | common in clinvar |
| Make rs11881222(A;G) |
| Make rs11881222(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 19 |
| Position | 39244283 |
| Gene | IFNL3 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs11881222 |
| dbSNP (classic) | rs11881222 |
| ClinGen | rs11881222 |
| ebi | rs11881222 |
| HLI | rs11881222 |
| Exac | rs11881222 |
| Gnomad | rs11881222 |
| Varsome | rs11881222 |
| LitVar | rs11881222 |
| Map | rs11881222 |
| PheGenI | rs11881222 |
| Biobank | rs11881222 |
| 1000 genomes | rs11881222 |
| hgdp | rs11881222 |
| ensembl | rs11881222 |
| geneview | rs11881222 |
| scholar | rs11881222 |
| rs11881222 | |
| pharmgkb | rs11881222 |
| gwascentral | rs11881222 |
| openSNP | rs11881222 |
| 23andMe | rs11881222 |
| SNPshot | rs11881222 |
| SNPdbe | rs11881222 |
| MSV3d | rs11881222 |
| GWAS Ctlg | rs11881222 |
| GMAF | 0.2576 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 19749757] Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C
[PMID 21070502] Interleukin-28B polymorphisms are associated with hepatitis C virus clearance and viral load in a HIV-1-infected cohort
[PMID 20887330] High sensitivity assay using serum sample for IL28B genotyping to predict treatment response in chronic hepatitis C patients.
[PMID 21389156
] The rs8099917 polymorphism, when determined by a suitable genotyping method, is a better predictor for response to pegylated alpha interferon/ribavirin therapy in Japanese patients than other single nucleotide polymorphisms associated with interleukin-28B.
[PMID 23866096] The predictive value of IL28B rs12979860, rs11881222 and rs8099917 polymorphisms and IP-10 in the therapeutic response of Egyptian genotype 4 patients
[PMID 24621321] Severe thrombocytopenia in a patient with inosine triphosphatase (ITPA)-CC genotype caused by pegylated interferon (IFN)-alpha-2a with ribavirin therapy: a case report
[PMID 23103287] IL28B polymorphisms are associated with severity of liver disease in human immunodeficiency virus (HIV) patients coinfected with hepatitis C virus.
[PMID 23135173] Analysis of IL28B alleles with virologic response patterns and plasma cytokine levels in HIV/HCV-coinfected patients.
| ClinVar | |
|---|---|
| Risk | rs11881222(G;G) |
| Alt | rs11881222(G;G) |
| Reference | Rs11881222(A;A) |
| Significance | Drug-response |
| Disease | peginterferon alfa-2b response - Efficacy ribavirin response - Efficacy peginterferon alfa-2a response - Efficacy |
| Variation | info |
| Gene | IFNL3 |
| CLNDBN | peginterferon alfa-2b response - Efficacy ribavirin response - Efficacy peginterferon alfa-2a response - Efficacy |
| Reversed | 0 |
| HGVS | NC_000019.9:g.39734923A>G |
| CLNSRC | |
| CLNACC | RCV000417140.1, RCV000417160.1, RCV000417187.1, |
