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rs7582141

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0 common in clinvar
Make rs7582141(G;T)
Make rs7582141(T;T)
ReferenceGRCh38 38.1/142
Chromosome2
Position159042977
GeneTANC1
is asnp
is mentioned by
dbSNPrs7582141
dbSNP (classic)rs7582141
ClinGenrs7582141
ebirs7582141
HLIrs7582141
Exacrs7582141
Gnomadrs7582141
Varsomers7582141
LitVarrs7582141
Maprs7582141
PheGenIrs7582141
Biobankrs7582141
1000 genomesrs7582141
hgdprs7582141
ensemblrs7582141
geneviewrs7582141
scholarrs7582141
googlers7582141
pharmgkbrs7582141
gwascentralrs7582141
openSNPrs7582141
23andMers7582141
SNPshotrs7582141
SNPdbers7582141
MSV3drs7582141
GWAS Ctlgrs7582141
Max Magnitude0
? (G;G) (G;T) (T;T) 28


GWAS snp
PMID [PMID 24974847]
Trait Response to radiotherapy in prostate cancer (toxicity)
Title A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24.1.
Risk Allele T
P-val 5E-11
Odds Ratio .37 [NR] unit increase


ClinVar
Risk rs7582141(T;T)
Alt rs7582141(T;T)
Reference Rs7582141(G;G)
Significance Drug-response
Disease radiotherapy response - Toxicity/ADR
Variation info
Gene TANC1
CLNDBN radiotherapy response - Toxicity/ADR
Reversed 0
HGVS NC_000002.11:g.159899489G>T
CLNSRC PharmGKB Clinical Annotation
CLNACC RCV000211418.1,