rs8176746
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (A;C) | Type B blood group (of ABO system); one allele | |
| (C;C) | 0 |
| Reference | GRCh38 38.1/142 |
| Chromosome | 9 |
| Position | 133255935 |
| Gene | ABO |
| is a | snp |
| is | mentioned by |
| dbSNP | rs8176746 |
| dbSNP (classic) | rs8176746 |
| ClinGen | rs8176746 |
| ebi | rs8176746 |
| HLI | rs8176746 |
| Exac | rs8176746 |
| Gnomad | rs8176746 |
| Varsome | rs8176746 |
| LitVar | rs8176746 |
| Map | rs8176746 |
| PheGenI | rs8176746 |
| Biobank | rs8176746 |
| 1000 genomes | rs8176746 |
| hgdp | rs8176746 |
| ensembl | rs8176746 |
| geneview | rs8176746 |
| scholar | rs8176746 |
| rs8176746 | |
| pharmgkb | rs8176746 |
| gwascentral | rs8176746 |
| openSNP | rs8176746 |
| 23andMe | rs8176746 |
| SNPshot | rs8176746 |
| SNPdbe | rs8176746 |
| MSV3d | rs8176746 |
| GWAS Ctlg | rs8176746 |
| GMAF | 0.123 |
| Max Magnitude | 0 |
| ? | (A;A) (A;C) (C;C) | 28 |
|---|---|---|
|
| ||
This SNP is a variant in the ABO gene, and is therefore potentially useful in determining ABO blood group, such as through the use of genosets. 23andMe reports this as a G/T while decodeme reports it as an A/C.
| GWAS snp | |
|---|---|
| PMID | [PMID 20139978] |
| Trait | Hematological and biochemical traits |
| Title | Genome-wide association study of hematological and biochemical traits in a Japanese population |
| Risk Allele | T |
| P-val | 4E-8 |
| Odds Ratio | 0.21 [NR] % variance |
[PMID 18464913
] A genome-wide association study identifies protein quantitative trait loci (pQTLs).
[PMID 18604267] Novel association of ABO histo-blood group antigen with soluble ICAM-1: results of a genome-wide association study of 6,578 women.
[PMID 20459687] Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring.
[PMID 21257350] DNA-based methods in the immunohematology reference laboratory.
[PMID 21306478] ABO blood group alleles and the risk of pancreatic cancer in a Japanese population.
[PMID 21680535] ABO genotype and the risk of gastric cancer, atrophic gastritis, and Helicobacter pylori infection.
[PMID 21792085] ABO blood group and chronic pancreatitis risk in the NAPS2 cohort.
[PMID 21832968] Pharmacogenetic predictors of angiotensin-converting enzyme inhibitor-induced cough: the role of ACE, ABO, and BDKRB2 genes.
[PMID 22258027] A common variant of the ABO gene protects against hypertension in a Spanish population.
